Early access to the Omnii research preview

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Our progress on the science of scaling, architecture and systems for general biological intelligence

  • Scaling data mixing for language and DNA pretraining

    Willie Neiswanger, Matthew Carter, Anvith Thudi, and Michael Poli · October 12, 2026

    We scale data mixing for language and genome models: thousands of sources derived from document behavior, and a Pareto frontier of mixtures over them.

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  • Christine Parthemore on joining Radical Numerics as Head of Biodefense

    Christine Parthemore · October 5, 2026

    Christine Parthemore joins Radical Numerics as Head of Biodefense, bringing two decades of experience at the U.S. Department of Defense and the Council on Strategic Risks.

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  • Genome language models can design cancer vaccines

    Alexander Fields, Michael Poli, and Eric Nguyen · September 8, 2026

    We post-trained Omnii, our next-generation genome language model, for end-to-end cancer vaccine design, from neoantigen selection to the final mRNA.

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  • Jacob Rinaldi joins Radical Numerics as Head of Scientific Strategy

    Radical Numerics · September 8, 2026

    Jacob Rinaldi joins Radical Numerics as Head of Scientific Strategy, bringing scientific depth from Genentech, Recursion, and Noetik to our work on general biological intelligence.

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  • Radical Numerics raises $50M seed to build general biological intelligence

    Eric, Michael, Stefano & Armin · June 15, 2026

    We've raised $50M to build general biological intelligence, and we're previewing Omnii, our next-generation genome language model for both human health and biodefense.

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  • A new era of biological threats, and the technology to defend against them

    Radical Numerics · June 15, 2026

    Omnii's first biodefense results, spanning paraphrased pathogen detection and fitness scoring of viral variants beyond standard methods.

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  • A new frontier in generative genomics with Omnii

    Radical Numerics · June 15, 2026

    A research preview of Omnii, our next-generation genome language model.

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  • NVFP4 pretraining: systems optimizations (Part 2)

    Jerome Ku and others at Radical Numerics · January 12, 2026

    A deep dive into TransformerEngine's implementation of the NVFP4 recipe: nvfp4 data flow, custom kernels, and systems optimizations for performant FP4 training.

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  • NVFP4 pretraining: from theory to implementation (Part 1)

    Jerome Ku, Michael Poli, and others at Radical Numerics · January 12, 2026

    NVIDIA's NVFP4 pretraining recipe: floating point fundamentals, the evolution of mixed-precision training, and the techniques that enable stable NVFP4 training.

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  • Phalanx: hardware-aligned sliding-window recurrences

    Garyk Brixi, Dragos Secrieru, Stefano Massaroli and others at Radical Numerics · October 14, 2025

    Phalanx: a drop-in replacement for sliding window attention. Faster and better quality. Hardware- and numerics-aware design of new layers that push the efficiency-quality frontier

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  • RND1: simple, scalable AR-to-diffusion conversion

    Keshigeyan Chandrasegaran, Armin W. Thomas and others at Radical Numerics · October 9, 2025

    Introducing RND1-30B, the largest open-source diffusion language model, trained via AR-to-Diffusion conversion with a simple, scalable recipe.

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