Solve

Biology

We’re a next-generation AI lab building toward general biological intelligence: AI that can interpret, generate, and predict biology.

DUAL MANDATE

Advance Biological Intelligence.
Strengthen Biodefense.

OUR MISSION

Solve Biology.

OMNII-1

28 Modalities Across Biology,
One Model.

SOTA genome language model

Introducing Omnii-1

Omnii-1 is a multimodal genome language model that learns across DNA, RNA, proteins, and other biological signals. It’s designed to predict the effects of genetic changes, generate sequences with desired functions, and guide new experiments.

One model to interpret, generate, and predict biology.

Explore Omnii

DUAL MANDATE

Advance Biological Intelligence. Strengthen Biodefense.

More capable biological AI could help us understand disease, design therapeutics, and create new biological functions. It also brings new risks.We’re advancing biological intelligence and strengthening biodefense together.

Advance Biological Intelligence

More capable biological AI could help us understand disease, design therapeutics, and create new biological functions.

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Biodefense

Assess what a sequence does, not just what it resembles. We partner with biodefense teams to strengthen defences against biological threats.

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Biology Is AI’s
Next Frontier

The challenge is to understand biology well enough to predict how it works and engineer what it can do. Solving it requires AI that learns directly from biological data, across systems and scales.

Our team helped pioneer long-context architectures with Hyena and generative genomics with Evo. With Omnii, we’re building on that foundation toward general biological intelligence.

What does it mean to Solve Biology? Watch the Film.

Radical Numerics' Mission is to Solve Biology.
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Advisors

  • George Church

    Harvard Medical School

  • Tri Dao

    Together AI

  • Paul Friedrichs

    Air Combat Command (Ret)

  • Eric Horvitz

    Microsoft

  • Jill Hruby

    Sandia National Labs

  • Chris Ré

    Stanford University

  • Ben Spector

    Flapping Airplanes

  • Andrew Weber

    Council on Strategic Risks

BACKED BY

  • Emergence Capital

  • Obvious Ventures

  • Triatomic Capital

  • Factory

  • First Spark Ventures

  • Patrick Collison

    CEO of Stripe

FEATURED IN

  • Fortune

  • TED

  • Nature

  • Science

  • Just AI

  • The New York Times

RESEARCH

Radical Numerics creates first AI-generated phages to reach human patient with Omnii-1

We trained Omnii-1 to generate viable phages, prioritize variants, and predict phage-host interactions. In a world first, Omnii-1-designed phages were administered to a human patient.

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Generative multiomic modeling with Omnii-1

Omnii-1 is a multimodal genome language model. It reconstructs held-out tracks, identifies the variants that change expression, splicing, and accessibility, and links enhancers to their target genes.

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JOIN US

Build AI's Next Frontier

Join us in advancing the foundations of AI, building toward General Biological Intelligence.